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Technical Assistant

Reference number : 2025-0083

Mainz

Vollzeit

Dermal Oncoimmunology

Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

The German Cancer Research Center (DKFZ) is the largest biomedical research center in Germany. With more than 3,000 employees, we run an extensive scientific program in the field of cancer research.

In the new Helmholtz Institute for Translational Oncology (HI-TRON) Mainz, the DKFZ cooperates with the Research Institute for Translational Oncology at the University Medical Center of Johannes Gutenberg University Mainz (TRON gGmbH), the Johannes Gutenberg University Mainz (JGU) and the University Medical Center Mainz. The aim of this partnership is to develop pioneering immunotherapies at HI-TRON and to identify new biomarkers for the effectiveness of the treatment.

For the Dermal Oncoimmunology Lab in Mainz we are seeking for as soon as possible a

The Dermal Oncoimmunology Lab (headed by Dr. Hafsa Munir) places fibroblasts at the centre of the immune-regulatory networks in cancer and autoimmunity. We aim to alter the state of fibroblasts in skin cancer towards an autoimmune-like state to induce robust anti-tumour immunity as a novel therapeutic strategy to treat cancer. We are using a combination of single cell proteomic (spectral flow cytometry and immunofluorescence) and genomic (RNA sequencing and spatial transcriptomics) to analyse the state of fibroblast-immune interactions in these disease contexts in primary patient samples and mouse models. We aim to utilise mouse models and complex 3D bioengineered organ-on-chips to analyse the effects of fibroblast manipulation on anti-tumour immunity. Our group is currently looking to recruit an outstanding and highly motivated technical assistant to support the development of this research program.

Your Tasks

We are looking to recruit a highly motivated and enthusiastic Biology Technical Assistant to join our research group. You will be a critical member of an international, collaborative team with opportunities to contribute to the sample preparation, assay development and analysis of data. The work involves performing cell and molecular biology techniques including multiparameter flow cytometry, immunofluorescence imaging, tissue processing, cell culture and gene / protein expression analysis. The successful candidate will also support perform animal experiments including performing inoculations, treatments, taking measurements and dissections. They will also contribute to laboratory organisation and management as well as participate in lab discussions. This work will also involve training other lab members in protocols developed.

Your Profile

Our group is searching for a highly motivated team player with excellent organisational and communication skills who can comfortably work in an international research environment. Training as a technical assistant (TA, BTA, MTA, CTA) or equivalent degree is required. Experience involving conducting and analysing experiments is essential. Proficiency in written and spoken German and English is also required for this position. Prior experience working with animals and performing animal husbandry is desired but not essential. You are open to learning a wide range of techniques and exploring multiple research fields.

We Offer

Excellent framework conditions : state-of-the-art equipment and opportunities for international networking at the highest level

30 days of vacation per year

Flexible working hours

Remuneration according to TV-L incl. occupational pension plan and capital-forming payments

Possibility of part-time work

Family-friendly working environment

Sustainable travel to work : subsidized Germany job ticket

Unleash your full potential : targeted offers for your personal development to further develop your talents

Our Corporate Health Management Program offers a holistic approach to your well-being

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