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Are you a talented and motivated life-science modelling & simulation scientist with experience in the pharma industry? Do you enjoy driving innovation and setting new boundaries in physiologically-based (PBPK / DDI) modelling ? This position offers you this and more exciting work in an innovative and fast-paced environment.

ESQlabs  is an innovative, internationally acting Contract Research Organization and a global leader in the development and application of the OSP Suite (www.open-systems-pharmacology.org). We are a research-focused provider of specialized computational analyses in the life sciences industry.

To help us grow our global PBPK / DDI impact , we are looking for a Senior / Principal Scientist Systems Pharmacology PBPK / DDI to strengthen our multi-disciplinary project teams for the successful completion of client goals.

Role

• Complement a dedicated high-performing team of scientists
• Collaborate with colleagues on multi-disciplinary teams to implement quantitative clinical pharmacology projects / programs and to provide clinical pharmacology and PBPK / DDI consultation to other company projects / programs
• Provide clinical pharmacology and pharmacometric consulting through advanced PBPK / DDI, and exposure-response modeling and simulation using the OSP-Suite (PK-Sim, MoBi, R), or other tools
• Support clinical pharmacology-related components of clinical study protocols, study conduct, data analysis, and report writing with the support of colleagues
• Responsible for appropriateness of methods, integrity of data used for analysis, and accuracy of results
• Regularly engage with clients regarding the strategic approach, project execution, presentation of results, regulatory implications, and messaging of findings
• Prepare final technical reports, synopses, executive summaries, and other regulatory documents
• Ensure the provision of advanced literature searches for project / program-related information
• Provide sophisticated written interpretation of material and integrate research findings into project / program methodology and results
• Share findings with internal and external project teams; prepare abstracts, presentations, and publication-ready manuscripts
• Provide mentoring and feedback to junior scientists
• Integrate knowledge of PBPK and DDI to provide guidance regarding proposed approaches to addressing drug development and regulatory approval challenges
• Expand scientific expertise through attendance and presentation at international, national, and regional scientific conferences, client meetings, and government meetings
• Develop and teach at OSP-Suite (PK-Sim, MoBi, R), and other workshops and courses

Required skills & experience

Education

Further qualities that will put you in the spotlight

What's in store for you

The dynamic team behind ESQlabs unites people with different backgrounds, spanning disciplines like pharmaceutical sciences, physics, bioinformatics, mathematics, data science, and software engineering. Our trust in each other, our open-mindedness, and our constant quest for excellence and innovation unite us. We value flat hierarchies, where everyone can contribute ideas and expertise to develop the best product. We are passionate, always willing to broaden our horizons, and love our start-up culture.

You will also benefit from :

About us

We collaborate with global corporations in the pharma and chemical industry, as well as start-ups in the life-science technology sector and academic and non-profit research institutions. We define new standards in pharmacometrics and systems pharmacology and toxicology areas. Our software and model platforms help scientists understand mechanisms of diseases and chemical toxicity to optimize individualized treatment of patients and protect the health of the animal and human life.

ESQlabs has attracted international players as sponsors for the OSP Software development. In addition, funding through national and EU-wide research grants allows us to develop our core technologies continuously.

For more information about our culture, values and benefits visit our  Unique career opportunities - ESQlabs GmbH .

At ESQlabs, we are committed to diverse backgrounds and experiences.