Talent.com

Senior Jobs in Ostrhauderfehn

Jobalert für diese Suche erstellen

Senior • ostrhauderfehn

Zuletzt aktualisiert: vor 2 Tagen
Senior / Principal Scientist Systems Pharmacology PBPK / DDI (m / f / d)

Senior / Principal Scientist Systems Pharmacology PBPK / DDI (m / f / d)

ESQlabs GmbHSaterland, Niedersachsen, DE
Quick Apply
Are you a talented and motivated.Do you enjoy driving innovation and setting new boundaries in.This position offers you this and more exciting work in an innovative and fast-paced environment.Contr...Mehr anzeigenZuletzt aktualisiert: vor über 30 Tagen
Sr Systems Network Engineer (m / f / d)

Sr Systems Network Engineer (m / f / d)

Disney ExperiencesPapenbourg, Allemagne
The Senior Systems Network Engineer configures, implements and supports all aspects of the network environment for the new Disney Cruise line ships. They provide technical expertise in resolving ope...Mehr anzeigenZuletzt aktualisiert: vor 5 Tagen
Bautechniker (m / w / d)

Bautechniker (m / w / d)

BUERO LERSCHLeer (Ostfriesland), Niedersachsen, DE
Über uns Ein führendes Unternehmen aus der Bau- und Ingenieurbranche sucht qualifizierte Bauleiter (m / w / d) für verschiedene Fachbereiche. Oberbauleiter (Projekt-Bauleiter, Senior-Bauleiter) 2.Baulei...Mehr anzeigenZuletzt aktualisiert: vor 2 Tagen
  • Gesponsert
(Senior) Mobile Entwickler Flutter (m / w / d)

(Senior) Mobile Entwickler Flutter (m / w / d)

eQ-3 Entwicklung GmbHLeer, Deutschland
Mehr anzeigenZuletzt aktualisiert: vor 10 Tagen
Pflegefachkraft (m / w / d)

Pflegefachkraft (m / w / d)

Emptio-Service-Gesellschaft mbHLeer, NI, DE
Hey du! Bist du auf der Suche nach einer erfüllenden Tätigkeit als Pflegefachkraft? Dann bist du bei uns genau richtig! Werde Teil unseres Teams!. Du wirst die Pflege und Betreuung unserer Bewohner : ...Mehr anzeigenZuletzt aktualisiert: vor über 30 Tagen
  • Gesponsert
Ausbildung Physiotherapeut (m / w / d)

Ausbildung Physiotherapeut (m / w / d)

Ludwig Fresenius Schulen LeerLeer (Ostfriesland), Niedersachsen, Deutschland
Als Physiotherapeut / in sorgst du dafür, dass jeder in Bewegung bleibt – vom Baby bis zum Senior, vom Büroangestellten bis zur Spitzensportlerin. Du bringst den Profifußballer nach dem Bänderriss wie...Mehr anzeigenZuletzt aktualisiert: vor über 30 Tagen
Senior HR Business Partner (m / w / d)

Senior HR Business Partner (m / w / d)

ORGADATA AGLeer, de
Bei ORGADATA haben wir alle unseren eigenen Kopf.Außergewöhnlich, direkt, präzise, zuverlässig.Eigenschaften, die unser Unternehmen genauso prägen wie unsere Produkte. Mit der Branchensoftware Logik...Mehr anzeigenZuletzt aktualisiert: vor 10 Tagen
Project Manager (m / f / d)

Project Manager (m / f / d)

Walt Disney ImagineeringPapenburg, Germany
Walt Disney Imagineering (WDI) is looking for a Project Manager who will report to the Senior, Principal or Executive Project Manager and is responsible for scope development, planning, budgeting, ...Mehr anzeigenZuletzt aktualisiert: vor über 30 Tagen
  • Gesponsert
(Senior) Mobile Entwickler Flutter (m / w / d) - Anwendungsentwicklung, Ingenieur

(Senior) Mobile Entwickler Flutter (m / w / d) - Anwendungsentwicklung, Ingenieur

eQ-3Leer, DE
Das sind Ihre Aufgaben bei uns.Sie arbeiten aktiv an der Anforderungsanalyse mit, definieren und realisieren Software-Prototypen auch in direkter Abstimmung mit unseren Produktmanagern, um frü...Mehr anzeigenZuletzt aktualisiert: vor über 30 Tagen
  • Gesponsert
Ausbildung : Physiotherapeut / in

Ausbildung : Physiotherapeut / in

Ludwig Fresenius SchulenLeer (Ostfriesland)
Als Physiotherapeut / in sorgst du dafür, dass jeder in Bewegung bleibt – vom Baby bis zum Senior, vom Büroangestellten bis zur Spitzensportlerin. Du bringst den Profifußballer nach dem Bänderriss wie...Mehr anzeigenZuletzt aktualisiert: vor über 30 Tagen
  • Gesponsert
(Senior) Produktmanager / Category Manager (m / w / d) – E-Commerce

(Senior) Produktmanager / Category Manager (m / w / d) – E-Commerce

ELV Elektronik AGLeer
Elektronik begeistert Sie, und Sie haben ein Gespür für Trends? Dann bringen Sie genau diese Leidenschaft und Ihre Erfahrung in unseren. Wir stehen für innovative Elektronik – von smarter Haustechni...Mehr anzeigenZuletzt aktualisiert: vor 4 Tagen
Diese Stelle ist in deinem Land nicht verfügbar.
Senior / Principal Scientist Systems Pharmacology PBPK / DDI (m / f / d)

Senior / Principal Scientist Systems Pharmacology PBPK / DDI (m / f / d)

ESQlabs GmbHSaterland, Niedersachsen, DE
Vor 30+ Tagen
Anstellungsart
  • Quick Apply
Stellenbeschreibung

Are you a talented and motivated life-science modelling & simulation scientist with experience in the pharma industry? Do you enjoy driving innovation and setting new boundaries in physiologically-based (PBPK / DDI) modelling ? This position offers you this and more exciting work in an innovative and fast-paced environment.

ESQlabs  is an innovative, internationally acting Contract Research Organization and a global leader in the development and application of the OSP Suite (www.open-systems-pharmacology.org). We are a research-focused provider of specialized computational analyses in the life sciences industry.

To help us grow our global PBPK / DDI impact , we are looking for a Senior / Principal Scientist Systems Pharmacology PBPK / DDI to strengthen our multi-disciplinary project teams for the successful completion of client goals.

Role

  • Complement a dedicated high-performing team of scientists
  • Collaborate with colleagues on multi-disciplinary teams to implement quantitative clinical pharmacology projects / programs and to provide clinical pharmacology and PBPK / DDI consultation to other company projects / programs
  • Provide clinical pharmacology and pharmacometric consulting through advanced PBPK / DDI, and exposure-response modeling and simulation using the OSP-Suite (PK-Sim, MoBi, R), or other tools
  • Support clinical pharmacology-related components of clinical study protocols, study conduct, data analysis, and report writing with the support of colleagues
  • Responsible for appropriateness of methods, integrity of data used for analysis, and accuracy of results
  • Regularly engage with clients regarding the strategic approach, project execution, presentation of results, regulatory implications, and messaging of findings
  • Prepare final technical reports, synopses, executive summaries, and other regulatory documents
  • Ensure the provision of advanced literature searches for project / program-related information
  • Provide sophisticated written interpretation of material and integrate research findings into project / program methodology and results
  • Share findings with internal and external project teams; prepare abstracts, presentations, and publication-ready manuscripts
  • Provide mentoring and feedback to junior scientists
  • Integrate knowledge of PBPK and DDI to provide guidance regarding proposed approaches to addressing drug development and regulatory approval challenges
  • Expand scientific expertise through attendance and presentation at international, national, and regional scientific conferences, client meetings, and government meetings
  • Develop and teach at OSP-Suite (PK-Sim, MoBi, R), and other workshops and courses

Required skills & experience

  • 5+ years (Principal 10+ years) of applied (pre-)clinical pharmacology experience
  • 3+ years (Principal 5+ years) of leading projects and programs
  • 3+ years (Principal 5+ years) of experience in regulatory applications of PBPK modeling in pre-clinical and clinical development
  • Good knowledge of regulatory requirements and guidelines for PBPK and DDI
  • Strong experience presenting scientific results to professional audiences
  • Extensive experience preparing, submitting, and receiving approval for publications in scientific journals
  • Mechanistic physiologically based pharmacokinetic modeling and simulation experience
  • Expert knowledge in domain-specific modeling software (e.g. PK-Sim® /  MoBi®, SimCyp®, or GastroPlus®)
  • Excellent communication, presentation, and leadership skills
  • Relationship-building skills with the ability to work closely with project leaders and team members
  • Strong organization skills and ability to handle multiple tasks simultaneously
  • Work well handling tight deadlines
  • Great critical-thinking and problem-solving skills
  • Fluency in English (oral and written), German is a plus
  • Education

  • PhD, or masters in quantitative sciences (Bioengineering, Applied Math, ...) with advanced (pre)clinical pharmacology related training or
  • PharmD or PhD in pharmacokinetics, clinical pharmacology, or related field with advanced applied mathematics related training
  • Further qualities that will put you in the spotlight

  • Experience in (IND / NDA) submissions
  • Advanced expertise in pharmacometric modeling software (e.g. NONMEM®, Monolix, or IQRtools)
  • Proficiency in a scripting language for modeling and simulation (ideally R, alternatively MATLAB®)
  • A strong understanding of statistics
  • Therapeutic domain knowledge : Diabetes, Oncology, Immunology or Inflammation
  • Published peer-reviewed articles
  • What's in store for you

    The dynamic team behind ESQlabs unites people with different backgrounds, spanning disciplines like pharmaceutical sciences, physics, bioinformatics, mathematics, data science, and software engineering. Our trust in each other, our open-mindedness, and our constant quest for excellence and innovation unite us. We value flat hierarchies, where everyone can contribute ideas and expertise to develop the best product. We are passionate, always willing to broaden our horizons, and love our start-up culture.

    You will also benefit from :

  • Flexible work hours and a home office policy that focuses on people and not on numbers
  • An attractive remuneration package
  • A dedicated budget for education programs and conferences you can attend
  • A working environment in which your contribution will make a difference, and that allows you to take ownership of projects and processes
  • Responsibility, autonomy, participation, and career perspective
  • About us

    We collaborate with global corporations in the pharma and chemical industry, as well as start-ups in the life-science technology sector and academic and non-profit research institutions. We define new standards in pharmacometrics and systems pharmacology and toxicology areas. Our software and model platforms help scientists understand mechanisms of diseases and chemical toxicity to optimize individualized treatment of patients and protect the health of the animal and human life.

    ESQlabs has attracted international players as sponsors for the OSP Software development. In addition, funding through national and EU-wide research grants allows us to develop our core technologies continuously.

    For more information about our culture, values and benefits visit our  Unique career opportunities - ESQlabs GmbH .

    At ESQlabs, we are committed to diverse backgrounds and experiences.