Regional Clinical Operations Manager.

Job Description

As Milestone One continues its global expansion, we are seeking an experienced Operations Manager to join our international team. This newly created role is critical to ensuring operational excellence across our regional activities and supporting the scalable, high-quality delivery of clinical research projects worldwide.

The Operations Manager will take full operational ownership of assigned regions, leading site operations, managing coordinator teams, and ensuring that clinical trials are executed efficiently, compliantly, and without disruption. This role requires a hands-on leader with deep knowledge of clinical trial operations who can proactively identify and resolve day-to-day challenges in a dynamic international environment.

This is a regional role, with the region to be assigned.

Key Responsibilities

Take end-to-end operational responsibility for clinical research projects within the assigned region.

Ensure effective execution of clinical trials in line with study protocols, timelines, quality standards, and regulatory requirements.

Oversee site qualification process and ensure smooth study start-up, including site contracting support, site activation, and coordination with internal and external stakeholders.

Lead, manage, and support regional teams of operational and BD staff.

Act as a mentor and escalation point for coordinators facing operational challenges.

Proactively manage risks, troubleshoot operational bottlenecks, and lead local resolution

Collaborate closely with internal global teams to ensure alignment, clear communication, and seamless project execution.

Monitor operational KPIs, prepare progress reports, and implement corrective actions where needed.

Represent Milestone One in operational discussions with sponsors, partners, and at selected industry meetings.

Qualifications

Minimum 5 years of experience in leading clinical trial operations within an SMO or CRO

Proven hands-on experience in managing clinical trial operations, including site start-up, contracting processes, and ongoing site management.

Strong understanding of clinical trial logistics, investigational product handling, and supply management.

Demonstrated experience in leading and developing teams of study coordinators or operational staff.

Ability to independently manage and resolve complex, real-time operational issues.

Excellent organizational, communication, and stakeholder management skills.

Fluent English

Experience working in an international and cross-functional environment.

Proactive, structured, and execution-focused leadership style.

Additional Information

Hybrid position (may require site visits)