StellenbeschreibungThe postdoctoral fellow will work in a team of enthusiastic biologists and medical scientists with the aim to identify networks in the regulation of human leukemia stem cell activity and to understand the mechanisms of developing and overcoming therapy resistanceFocus on epitranscriptomic modifications and gene expression with regulation of translation in cancerMulti-Omics single cell sequencing approaches to characterize therapy resistanceResponsible planning and performing of experiments in the framework of the scientific project planPreparation and presentation of project reports and publicationsPhD in biology, biochemistry or equivalentBroad expertise in basic cell-molecular and biochemical techniques (Western blotting, immunoprecipitations, ChIP, gene expression analysis, cloning, cell culture, lentiviral transductions, flow cytometry, microscopy etc.)Experience and skills in Next-Generation-Sequencing, CRISPR / CAS9, shRNA-mediated knock down and genome editing techniquesExperience in writing scientific reports and papersVery good knowledge of and experience with MS office, graphic programs, statistical software, bioinformatics tools and online tools ( Illustrator, Lightroom, GraphPadPrism, R, BLAST)Fluent both in written and spoken English languageGoal-oriented, individual training and development opportunitiesWorking with the latest techniques / technical equipmentPossibility of mobile workingPossibility to publish scientifically is offered and supportedRegular team meetingsInterdisciplinary cooperationFlexible working hours within the framework of flexitimeCollectively agreed remuneration (TV-L E13), attractive company pension scheme (VBL)30 days vacationSustainable travel : job ticketFamily-friendly working environment : cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of careWide range of health, prevention and sports offers