PhD Student in the field of tumor immunology and T cell based immunotherapies (m/f/d)
The research group of Jun. Prof. Natalie Köhler, PhD, Department of Internal Medicine I (Hematology, Oncology and Stem Cell Transplantation), University Medical Centre Freiburg and Centre For Integrative Biological Signalling Studies (CIBSS), University of Freiburg, is currently looking for a highly motivated
PhD Student in the field of tumor immunology and T cell based immunotherapies (m / f / d)
Our laboratory focusses on the identification of novel targets for immunotherapies in hematological malignancies, in particular key regulators of immune checkpoint molecules.
Furthermore, we aim to elucidate the mechanisms of and find novel therapeutic options for cancer immunotherapy-related adverse events.
To this aim, we use classical genetic mouse models and T cell characterization approaches as well as novel NGS-based technologies, in particular single-cell RNA and immune receptor sequencing with an in-lab 10X Genomics system.
The offered PhD project will focus on the elucidation of the immune and molecular mechanisms driving graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
We offer you :
- an enjoyable and collaborative laboratory atmosphere with intensive mentorship
- the opportunity to employ a wide variety of modern methods in cell-, protein- and molecular biology
- a motivated research group
- a translational project with clinical relevance
- a dynamic and highly multidisciplinary research environment
- a doctoral position (TV-L 65%) in a 3-year research project
Your skills and qualities :
- excellent Master’s degree in molecular medicine, immunology, molecular biology or a related field
- experience in immunologic and cancer research
- interest and knowledge in immunology and transplant biology
- hands-on experience in cell culture and in vitro / ex vivo immunological assays
- experience with in vivo models and FELASA certificate
- experience in single cell transcriptomics and data analysis are a plus
- intrinsic motivation and the ability to work in a team
- ability to work independently
- fluency in written and spoken English
The position is limited to 3 years.
Please submit your application online (see Apply now button) including a letter of motivation, your CV, copy of graduation certificates and University grades and one or two letters of reference.
We are very much looking forward to your application.
University Medical Center Freiburg
Department of Internal Medicine ICentre für Translational Cell Research (ZTZ)
Natalie Köhler, PhD
Hugstetter Str. 55, 79106 Freiburg
Should you have any further questions, please contact :
Dr. Natalie Köhler [email protected] (please do not send any
application to this address) General information : Salary is assigned according to a pay scale. Unless prevented by operational or legal reasons, full-time positions are generally open to those wishing to job share.
Where two candidates are equally suitable for a post, severely disabled candidates are given priority. Employment decisions are made by the Personnel Department.
PhD student (f/m/d) in Ulm
The applicant will employ complex 3D co-culture model systems, genetically engineered mouse models as well as human organoid models to perform shRNA and CRISPR library-based screening approaches and study biochemical and biophysical aspects of tumor-niche interactions for entering clinical translati...
Duales Studium - Handel (Bachelor of Arts) (m/w/d) - In 3 Minuten erfolgreich bewerben
Gestalte deine Zukunft aktiv mit uns! DUALES STUDIUM - HANDEL (BACHELOR OF ARTS) (M/W/D) DEINE AUFGABEN: * Kennenlernen der Themen Verkauf, Sortiment und Prozesse * Unterstützung. Starte dein duales Studium mit uns und eigne dir das theoretische Wissen an, um die Prozesse sofort im Arbeitsalltag nac...
PhD Position (f/m/div) Partners in Crime
The Department of Criminology at the MPI-CSL offers a highly interdisciplinary and dynamic research environment in which criminologists, psychologists, sociologists, mathematicians, and computer scientists work together to understand the causes and consequences of criminal behavior and to develop ef...
Thesis "Simulation of reaction and separation processes in the Power-to-Liquids context"
Would you like to play an active role in shaping the energy transition and gain practical experience during your studies? With us, you will work in a dynamic and motivated team on a forward-looking topic in the field of renewable energies. For the energy-efficient and economical production of sustai...
Junior Regulatory Controller in Trustee & Depositary- Associate, Fund/Client Accounting I
BNY Mellon offers an exciting array of future-forward careers at the intersection of business, finance, and technology. We are one of the world's top asset management and banking firms that manages trillions of dollars in assets, custody and/or administration. Known as the “bank of banks” - % of the...
Professor (W3) for translational research on microbiota and the immune system with focus on gastrointestinal oncology (f/m/d)
no management responsibilities in Ulm
The applicant should have an independent research profile, proven by successful third-party funding and high-ranking publications in basic and/or translational research in the field of microbiota and immune system with a focus on oncology, as well as the ability to transfer research results into cli...
(Senior) Manager/Expert of SAP S/4HANA Finance in Insurance and Banking
Karriere nach Maß, das heißt für uns: Individuelle Entwicklungsmöglichkeiten in Deine Richtung und Deiner Geschwindigkeit. Damit sind Deine individuellen Ziele und die Wavestone Unternehmensziele perfekt aufeinander abgestimmt. Respekt, Wertschätzung und höchste Professionalität sind die Grundpfeile...
PhD student (f/m/d) in Ulm
The applicant will employ complex 3D co-culture model systems, genetically engineered mouse models as well as human organoid models to perform shRNA and CRISPR library-based screening approaches and study biochemical and biophysical aspects of tumor-niche interactions for entering clinical translati...
Hardware Developer (working student - on site) - Join the Revolution in Life-Science Robotics at goodbot
Tasks Design, develop, and test hardware components for goodbot Collaborate with the front-end development team to ensure seamless hardware-software integration Work independently and take ownership of your tasks and projects Devise smart, custom solutions that fit our robot Learn and engage in vari...
Thesis »Investigation of the thermomechanical behaviour of a forged steel for use in large turbines«
With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. At the Fraunhofer IWM, 330 employees conduct research on materials and components with...