Principal Associate - Mass Spectrometry for Gene Therapy

The Position

Are you looking for a new scientific challenge?

In Roche’s Pharmaceutical Cell & Gene Therapy organization (PTC), we are united by our vision to drive and realize cell and gene therapies by translating scientific progress into life-changing experiences for patients.

Our core business is to bring game-changing viral vector based therapies from early clinical supply into the market to serve patients with an unmet clinical need to cure diseases.

We are doing this by developing world-class recombinant adeno-associated virus vectors (rAAVvs) manufacturing processes using cutting-edge technology for the whole value chain.

Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to make extraordinary life-changing gene therapies a reality for the patients.

The position

As a Principal Associate Mass Spectrometry for Gene Therapy (m / f / d) you will join an expert team in the area of analytical development for viral vector based therapies.

The main objective of your work is the chromatographic and mass spectrometric (LCMS) analysis of rAAVvs to support process development, improve our knowledge about our molecules and bring projects from the preclinical phase to market.

You will also develop and employ cutting-edge technologies to enable extended characterization of rAAVv capsids.

Your impact

Your main task comprises the self-responsible analysis of samples to support bioprocess development including data evaluation and reporting

Furthermore, you make a difference by adapting existing as well as developing new analytical methods for detailed characterization of rAAV capsids

The self-responsible documentation, execution, and evaluation of analyses according to GMP guidelines also belongs to your tasks

You take over the independent preparation of development reports and method qualification reports

Besides, we ask for your support in handling the testing, establishment, qualification, and supervision of modern LC-MS( / MS) systems

Your profile

You have at least five years of experience in protein analysis via chromatographic and mass spectrometric methods. Besides, knowledge in respective data evaluation is required.

You also have some first experience with proteomics analysis

The independent preparation of reports of different kind is nothing new to you method development, qualification). This also includes the discussion of data with other experts.

A Bachelor / Master’s degree in biotechnology, biology, chemistry or a similar area is the foundation of your knowledge

Fluency in English, written and spoken, is natural to you and we can trust in your structured, independent, and responsible way of working while tackling complex topics

This position is limited to a period of 3 years.

We look forward receiving your application!

The application documents

For your application, please keep it simple. We only ask you for an up-to-date CV. All further documents will be handled at a later stage.

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