Principal Engineer (d/f/m)

Why us? We believe that AI has the potential to revolutionize how cancer and other complex diseases are diagnosed and treated. We also believe that AI is a tool, not an identity – without access to high-quality data and a scientifically rigorous, transparent approach to model development, AI is just a buzzword. That's where we come in. Aignostics is a spin-off from one of Europe's largest and most prestigious university hospitals (Charité), with employees in Berlin and New York. We have received over $50M in funding from leading investors and are a growing team of over 100 interdisciplinary professionals. We work with academic partners as well as leading global life sciences companies. As a Principal Engineer at Aignostics, you will play a crucial role in shaping the technical direction and architectural integrity of our technical platform and products. You will work hand in hand with our collaborators in academia and industry to push the state of the art for digital pathology. Your expertise will be instrumental in driving technical excellence across all engineering teams, ensuring we deliver high-quality, scalable solutions that transform complex biomedical data into actionable insights for cancer research and diagnostics. You will report directly to our Sr. Vice President of Product & Engineering. This is a unique opportunity to join a fun, diverse, and growing team of 100+ software engineers, applied scientists, biologists, and pathologists to shape the next generation of cancer treatments. You will be part of a driven community that works in an agile, supportive, and interdisciplinary research environment where your results make a difference to patients. In our established startup, you have the opportunity to grow personally and technically, take on significant responsibilities, and benefit from a dynamic work environment. At Aignostics, we believe that fighting cancer is a job for people of all identities, backgrounds, and cultures. We value and celebrate diversity and inclusion and are committed to offering equal employment and promotion opportunities for all applicants and employees. Where your expertise is needed Own the technical direction and architectural integrity of our platform Advise our CTO and Sr. Vice President of Engineering on the technical vision of Aignostics Align our technical strategy with business objectives to provide a competitive advantage Resolve technical conflicts across teams and harmonize technologies to unlock synergies Advise product management on technical feasibility, cost, and risks of complex product features Drive technical design, planning, and integration of our platform across systems Provide technical guidance in system design reviews for all teams Educate senior and mid-level engineers to bring them up to the next level Demonstrate long-term thinking and utmost technical excellence in your individual contributions Lead the technical strategic planning and execution across the TechOrg's quarterly roadmap Champion the drive for the highest standards across engineering teams Drive yearly operational readiness reviews of our systems, collaborating with owning teams Guide engineering teams in maintaining up-to-date, high-quality documentation and code What we are looking for Advanced degree in Computer Science, Software Engineering, or a related field 10+ years of software development experience, with at least 5 years in senior technical leadership roles Proven track record of driving technical excellence and innovation in organizations with 50+ engineers Excellent communication skills, able to articulate complex technical concepts to both technical and non-technical stakeholders Solid background in large scale systems and software architecture, design patterns, and clean coding Extensive experience in designing and implementing large-scale, distributed and event-driven systems Extensive experience with data processing at scale Extensive expertise in multiple programming languages and frameworks Deep understanding of cloud technologies (GCP, AWS), containerization and orchestration (Kubernetes) Familiarity with DevSecOps and MLOps practices, complex CI/CD pipelines, and infrastructure as code Ideally, you also: Have experience with machine learning at scale Contribute to open-source projects and technical publications Have experience with frontend engineering and typescript Worked in a regulated environment, e.g. financial services, aerospace or healthcare Have knowledge of digital pathology or medical imaging Have experience with biomedical data processing and analysis We are still keen to hear from you if you don't match all the above points! Our needs are diverse and growing, and you are encouraged to apply if you have a strong combination of these skills. Our offer Join a purpose-driven start up: We are working collectively to fight cancer and improve patient outcomes. Come help us make a difference! Cutting-edge AI research and development, with involvement of Charité, TU Berlin and our other partners Work with a welcoming, diverse and highly international team of colleagues Opportunity to take responsibility and grow your role within the startup Expand your skills by benefitting from our Learning & Development yearly budget of 1,000 € (plus 2 L&D days), language classes and internal development programs Mentoring program, you’ll learn from great experts Flexible working hours and teleworking policy Enjoy your well-deserved time off within our 30 paid vacations days per year We are family & pet friendly and support flexible parental leave options Pick a subsidized membership of your choice among public transport, sports and well-being Enjoy our social gatherings, lunches, and off-site events for a fun and inclusive work environment Optional company pension scheme Join us to make a difference! #LI-PX1