PostDoc in Precision Immunotherapy / Antibody Engineering

Scope of duties

As a PostDoc in the research group of Prof. Christoph Klein, you will join a translational research program and with the option to take on a leadership role.

You will be involved in a precision immunotherapy program based on an innovative conditional strategy (“AND-GATE”) to target cancer and immune cells. This includes the engineering, production and purification of novel recombinant antibody formats, the setup and optimization of in vitro and in vivo functional assays, and the further development of our iPSC-derived organoid system for patient-specific therapy testing.

You will help plan and coordinate ongoing experiments, prepare scientific data for publication and grant applications, and support the scientific supervision of junior researchers.

Our requirements

• Completed PhD in Biology, Biochemistry, Biotechnology or a comparable field

• Solid experience in the following areas:
• Antibody engineering, protein expression and purification FPLC)
• Molecular biology and cell biology techniques
• iPSC cultivation and/or differentiation into immune cell types
• Experience with in vitro or in vivo functional assays and multi-omics data analysis is an advantage
• The ability to work independently, as well as in an interdisciplinary and international team
• A structured, meticulous and solution-oriented working style
• Excellent English skills; German skills are an advantage

Our offer

• The position is initially funded for two years . Subject to a positive scientific re-evaluation, an extension is possible

• An innovative and challenging position within the research group of Prof. Christoph Klein, operating at the interface of translational immunotherapy, stem cell biology and precision medicine.
• An international and interdisciplinary research environment, supported by close collaboration with academic and industrial partners within an established research network
• Close collaboration with basic scientists, bioinformaticians and clinician scientists on two complementary translational projects
• A collaborative, supportive and inspiring working environment that encourages scientific independence
• Employment according to the German public-sector collective agreement (TV-L), including annual leave and additional benefits in accordance with the applicable regulations