Director Program Management

Tubulis is dedicated to developing novel, effective, and safe therapies for the treatment of cancer — one of the most pressing challenges in modern medicine. Our mission is to become a leading company in targeted therapeutics and antibody–drug conjugates (ADCs). With a passionate team, proprietary technologies, and innovative therapeutic concepts, we are ushering in a new era in the fight against cancer.

Join a multidisciplinary, highly focused group working to deliver promising ADCs to patients with solid and haematological cancers.

Position Overview

We are seeking a proactive and committed Director, Program Management to provide strategic leadership and operational excellence for TUB-040, Tubulis’ lead program, as well as for our portfolio of innovative therapeutic programs spanning early- and late-stage clinical development.

The Director will partner closely with leaders in Clinical Development, Regulatory, CMC, Biomarkers, PK, Nonclinical, Commercial, and other functions to ensure timely delivery of key milestones, robust risk management, and smooth progression of programs toward regulatory approval and commercialization.

The role reports to the Vice President, Program Management.

Key Responsibilities

• Lead the cross-functional TUB-040 program team through all stages of clinical development — from IND-enabling studies to pivotal trials and regulatory submissions.
• Serve as the primary point of contact for program strategy, planning, execution, and milestone delivery.
• Develop and maintain integrated program plans, budgets, timelines, and risk management strategies aligned with corporate objectives.
• Partner with functional leaders (Clinical Development, Clinical Operations, Regulatory, CMC, Biostatistics, Biomarkers, Commercial, etc.) to ensure requirements are well-defined, resourced, and executed with quality.
• Drive effective decision-making by preparing clear program updates and recommendations for governance committees.
• Provide mentorship within the Program Management function, fostering process improvements and building organizational capabilities.
• Encourage collaboration, guide team members, address challenges, and promote a positive working environment.
• Maintain open communication with the VP Program Management, team members, partners, and key stakeholders.

Candidate Profile

• Bachelor’s or advanced degree in a relevant scientific discipline.
• 10+ years of experience in the biotechnology or pharmaceutical industry, with significant program/project management leadership.
• Demonstrated success advancing programs through multiple phases of clinical development (IND/CTA, Phase I–III, BLA/MAA, launch, lifecycle management).
• Proven expertise in late-stage development and pivotal trials.
• Comprehensive knowledge of clinical development, regulatory requirements, GxP, CMC, nonclinical, and commercialization aspects.
• Strong leadership, organizational, and interpersonal skills with the ability to inspire and motivate cross-functional teams.
• Excellent communication and presentation skills; able to synthesize complex data and present compelling updates to leadership and stakeholders.
• Proficiency with project management tools (MS Project, Excel, PowerPoint, Think-Cell).
• Self-starter with strong problem-solving skills; comfortable working in a fast-paced, dynamic environment.
• Fluent English (written and spoken); German is a plus.

Why Join Us

• Flat hierarchies and short decision-making processes.
• Open corporate culture with mobile working options.
• Unlimited contract following probation, plus 30 days of vacation.
• Mobility allowance, modern technology, and a pleasant office environment.
• Strong team spirit, appreciation of individual contributions, and regular team events.
• Work alongside a multicultural, global team passionate about advancing next-generation cancer therapies.