Application deadline : December 15, 2024
The University Hospital Würzburg is seeking a motivated and talented PhD student (m / f / div) to join the Emmy Noether Research Group led by Dr. Zoltan Nagy at the Institute of Experimental Biomedicine . Be part of a dynamic research group and investigate fundamental mechanisms in hematology!
In this DFG-funded project, you will work at the forefront of megakaryocyte biology, leveraging state-of-the-art technologies, including single-cell transcriptomics, CRISPR gene editing, transgenic mouse models, and advanced imaging techniques.
PhD Position (m / f / div)
in Megakaryocyte Biology
Your tasks :
- designing and performing single-cell RNA sequencing experiments, applying advanced data analysis to identify novel regulatory mechanisms
- conducting in vivo studies in mouse models, focusing on experimental hematology techniques to investigate and modulate platelet biogenesis
- carrying out in vitro cell culture experiments, utilizing stem cell differentiation protocols and CRISPR-based gene editing to manipulate and study megakaryocyte function
- performing innovative biochemical experiments, including advanced immunoblotting, to dissect key signaling pathways involved in megakaryocyte development
- presenting research findings at project meetings and conferences, and contribute to peer-reviewed publications
Your profile :
a master’s degree in biochemistry, cell biology, molecular biology, hematology, or a related fielda strong foundation in molecular and cellular biology, with hands-on experience in cell culture and techniques such as microscopy, flow cytometry, or Western blottinginterest in bioinformatics, including single-cell RNA-seq data analysis, and computational skills, such as experience with data analysis tools (e.g., GraphPad) or programming languages like R, would be an advantagedemonstrated scientific rigor, curiosity, and a willingness to learn and apply new methodsstrong motivation and communication skills with proficiency in written and spoken English demonstrated through a language exam, thesis work, publications, or conference presentationsWe offer :
You will have access to cutting-edge laboratory facilities, including single-cell platforms, high-resolution imaging systems, and automated immunoblotting technologies.You will contribute to an exciting research project based on a recently discovered signaling pathway crucial for megakaryocyte maturation.You will receive comprehensive training in molecular, cellular, and data analysis methods.We offer personalized mentoring and a collaborative environment designed to support your professional growth.This is what you can look forward to :
training and continuing educationretirement pension planflexible working hourscollegialitysport and fitness optionsemployee eventscorporate benefits