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Ph.D. Researcher Cell Painting for Ecotoxicology (all genders)

BayerMonheim, North Rhine Westfalia, DE

Vor 30+ Tagen

Stellenbeschreibung

Where do you want to go? What do you want to achieve? How would you like to get involved? The choice is yours and we will support you on your way. At Bayer, multi-talents and specialists, visionaries and passionate people, thinkers and doers come together to feed the world, slow climate change and create healthier, more sustainable lives for all. This is the opportunity to start your career with a global leader committed to #HealthForAll #HungerForNone. Bring your ideas, skills and passion with you. Your career starts here.

Cell Painting is a high-throughput image-based screening method used frequently in drug discovery. It’s application to environmental chemicals has been established. So far nearly all studies were conducted using human cell lines with the aim to predict toxicity to humans. In this project, Bayer Crop Science and the Helmholtz Centre for Environmental Research (UFZ) (High-throughput ecotoxicology group, Dr. Jo Nyffeler) teamed up to explore the applicability of Cell Painting assays on cell lines from diverse species for characterization of the environmental safety profile of plant protection products. This PhD position offers an opportunity to develop and characterize innovative in vitro ecotoxicological methods for plant protection products at the interface of academic research and industry application.

YOUR TASKS AND RESPONSIBILITIES

You conduct literature work and design and execute your experiments independently
Develop, implement and perform Cell painting assay with different cell lines
Conduct cell culture, assay development and measurements in the laboratory
Perform miniaturized in vivo experiments with daphnia or algae
Communicate the obtained results in internal and external meetings (e.g. conferences) and via publications

WHO YOU ARE

You have a Master’s degree in cell biology, biochemistry, ecotoxicology or a related field

You bring a strong background in cell culture and basic skills in a programming software (e.g. R)

Experience with cell-based assays, fluorescence microscopy and data science are a plus

You work detail-oriented and are enthusiastic about the project

You have the ability to work independently as part of a collaborative, interdisciplinary team at two project partners (Bayer AG & UFZ)

You have excellent written and verbal communication skills in English

WHAT WE OFFER

Full-time 4-year Ph.D. position with a competitive salary

Opportunity to work with leading experts in Cell Painting and Alternative Methods for Ecotoxicology

Access to state-of-the art laboratory facilities

Participation in the graduate school HIGRADE at the Helmholtz Centre for Environmental Research (Leipzig)

We support your professional growth by providing access to learning and development opportunities, training programs, development dialogues as well as coaching and mentoring programs

Ever feel burnt out by bureaucracy? Us too. That’s why we’re changing the way we work— for higher productivity, faster innovation, and better results. We call it Dynamic Shared Ownership (DSO). Learn more about what DSO will mean for you in your new role here :

This position is a four-year temporary project position. The work will be performed in Leipzig at the Helmholtz Centre for Environmental Research (UFZ). Please apply online by submitting a cover letter, CV and relevant certificates in one file. We are looking forward to meeting you!

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