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PhD Student Biology, Chemistry (m / f / d)

Martin-Luther-Universität Halle-WittenbergDessau-Roßlau, Sachsen-Anhalt, Germany

Vor 20 Stunden

Stellenbeschreibung

The Medical Faculty of the Martin Luther University Halle-Wittenberg invites applications for seven positions within the mikroPank research consortium. This interdisciplinary initiative is dedicated to developing preclinical, patient-specific models to advance personalized treatments for pancreatic cancer patients.

Research Assistant / PhD Student (m-f-d)

E 13, 65 %)

We are hiring :

Three PhD students (E13, 65%), reference number : 7-242 / 24-D

All positions are available immediately and are temporary, until December 31, 2027.

About the mikroPank consortium :

The consortium is deticated to creating 3D tumor models from primary, patient-derived tumor cells and components of the tumor microenvironment, such as fibroblasts, adipocytes, and immune cells. These models replicate the patient-s tumor in-vitro to study mechanisms of drug resistance using advanced technologies, including single-cell RNA sequencing (scRNA-seq) and CRISPR-based genome editing. By integrating natural sciences and clinical expertise, the consortium aims to advance research towards innovative, personalized therapies for pancreatic cancer patients.

Work Tasks :

Cultivation of pancreatic tumor organoids and cells of the tumor microenvironment

Single-cell RNA sequencing (scRNA-seq)

Genetic manipulation of cells using CRISPR

Independent project management

Participation in national and international collaborations

Opportunity for own scientific qualification

Requirements :

Completed scientific university degree in the field of life sciences (Master)

Experience with cell culture techniques, ideally experience in the culture of pan-creatic tumor organoids

Knowledge of lentiviral transduction

Practical experience with single-cell RNA sequencing (scRNA-seq)

Programming experience in R is an advantage

Scientific processing, presentation and publication of achieved results

Very good written and spoken English language skills

Analytical and problem-oriented thinking

Structured and thorough way of working

Ability to work in a team

What We Offer :

Collaborative research environment with communication in English

Access to state-of-the-art equipment, facilities and resources

Opportunities for national and international collaborations and conference visits