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Senior Scientist Computational Modeling mfd
ESQlabs GmbHCloppenburg, Lower Saxony, Germany- Gesponsert
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Universität VechtaVechtaSenior Scientist Computational Modeling mfd
ESQlabs GmbHCloppenburg, Lower Saxony, GermanyAre you a talented and motivated scientist with a strong background in mathematics engineering or physics Do you have a pa ssion for applying computational methods to lifescience data particularly in the field of organonachip (OoC) Microphysiological Systems (MPS) or 3D cell cultures Are you adept at programming for biological data analysis AI / ML and data interpretation
Do you also share our vision of bridging the gap between advanced microphysiological systems and realworld clinical outcomes through innovative computational modeling Then MPSlabs invites you to consider joining our growing and innovative team!
MPSlabs is at the forefront of integrating biological data from cuttingedge microphysiological systems organonchips and 3D spheroids with advanced computational modeling (such as physiologically based pharmacokinetics PBPK and quantitative systems pharmacology or toxicology QSP & QST) to accelerate drug discovery and development. We partner with leading organizations to explore new therapeutic frontiers and revolutionize how preclinical testing is conducted.
To continue driving innovation in this rapidly evolving domain we are looking for a Senior Scientist Computational Modeling (m / f / d) who will contribute to our diverse crossfunctional projects. This role will involve everything from experimental data interpretation and advanced analytics to computational modeling and simulation for PBPK AI / ML and beyond.
Role
- Join a dedicated highperforming team of scientists engineers and computational biologists working on integrative MPS projects.
- Collaborate across multidisciplinary teams to design and implement quantitative strategies for analyzing and interpreting preclinical and clinical data.
- Develop refine and apply computational approaches (e.g. PBPK PK / PD translational modeling and data analysis) to support drug discovery efforts.
- Provide pre and clinical pharmacology and pharmacometric consulting through advanced QSP and PBPK and exposureresponse modeling and simulation using the OSPSuite (PKSim MoBi R) or other tools
- Collaborate with colleagues on multidisciplinary teams to implement quantitative clinical pharmacology projects / programs and to provide clinical pharmacology and QSP / PBPK consultation to other company projects / programs. Develop refine and apply stateoftheart AI / ML approaches (e.g. random forest neural networks PCA) to bridge knowledge gaps complementing mechanistic modeling approaches
- Develop R frameworks for data analysis pipelines and integrate findings within the OSPsuite
- Contribute to the design and analysis of experiments and studies; engage in data interpretation and communication of results.
- Serve as a key liaison between laboratory scientists and computational / modeling experts ensuring robust data generation and analysis.
- Prepare and present project updates final technical reports synopses executive summaries and other regulatory documents.
- Assure appropriateness of methods integrity of data used for analysis and accuracy of results
- Regularly engage with clients regarding the strategic approach project executionpresentation of results regulatory implications and messaging of findings
Required skills & experience
Education
Further qualities that will put you in the spotlight
Whats in store for you
At MPSlabs you will join an innovative and multidisciplinary team that combines stateoftheart microphysiological systems with cuttingedge computational modeling. We pride ourselves on fostering a collaborative environment driven by creative thinking open communication and continuous learning .
You will also benefit from :
Interested
We encourage you to apply and look forward to potentially welcoming you to our dynamic MPSlabs team!
About us
We collaborate with global corporations in the pharma and chemical industry as well as startups in the lifescience technology sector and academic and nonprofit research institutions. We define new standards in pharmacometrics and systems pharmacology and toxicology areas. Our software and model platforms help scientists understand mechanisms of diseases and chemical toxicity to optimize individualized treatment of patients and protect the health of the animal and human life.
ESQlabshas attracted international players as sponsors for the OSP Software development. In addition funding through national and EUwide research grants allows us to develop our core technologies continuously.
For more information about our culture values and benefits visit ourUnique career opportunities ESQlabsGmbH.
At ESQlabs we are committed to diverse backgrounds and experiences.
Key Skills
Laboratory Experience,Mammalian Cell Culture,Biochemistry,Assays,Protein Purification,Research Experience,Next Generation Sequencing,Research & Development,cGMP,Cell Culture,Molecular Biology,Flow Cytometry
Employment Type : Full Time
Experience : years
Vacancy : 1